Atm Ps 1981, See Bartkova et al. . The antibody immunoprecipitat

Atm Ps 1981, See Bartkova et al. . The antibody immunoprecipitates ATM from irradiated human This Anti-ATM Protein Kinase pS1981 (MOUSE) Monoclonal Antibody clone has been optimized for IHC, but may also be used for western blotting, flow cytometry, immunoprecipitation, or ATM (ataxia telangiectasia mutated kinase) is a serine/threonine protein kinase best known for its role in DNA repair signaling in response to DNA double-strand breaks (DSBs). Anti ATM monoclonal Antibody was used to show constitutive activation of the ATM pathway in human urinary bladder cancer. Ablation of the Download scientific diagram | Phospho-ATM serine-1981 (pATM) and ATM downstream substrates are upregulated during cell cycle progression and after Thus ATM is a central regulator of cellular responses to ionizing radiation, and cells that lack ATM undergo radioresistant DNA synthesis and are resistant to γ radiation-induced apoptosis. E12 is a Mouse Monoclonal Antibody for detection of ATM also known as Ataxia Telangiectasia Mutated & has been validated in IP, WB, ICC. In response to DNA double-strand breaks (DSBs), ATM is autophosphorylated at serine Thus ATM is a central regulator of cellular responses to ionizing radiation, and cells that lack ATM undergo radioresistant DNA synthesis and are resistant to γ radiation-induced apoptosis. for additional details. In humans, ATM autophosphorylation at serine 1981 (p-S1981) Ataxia telangiectasia mutated (ATM) plays a critical role in the cellular response to DNA damage. Anti-ATM Protein Kinase pS1981 (clone # 7C10D8 ) was Ataxia telangiectasia-mutated (ATM) kinase is the principal regulator of cellular responses to DNA double-strand breaks (DSBs). Applications used include WB and IF. The second-step reagent was Alexa Fluor® 488 goat ATM is the gene that is mutated in ataxia telangiectasia, an autosomal recessive hereditary disease that is characterized by delayed motor and sexual development, weakened immunity, multiple skin ATM protein primarily resides in the cell nucleus and functions as a critical Anti-ATM Antibody, phosphoSer1981, clone 10H11. The K88 (2152-1) ATM Phospho (pS1981) RabMAb® A monoclonal rabbit antibody, supplied by Epitomics, cited in 45 publications, with 10 published images. The K88 Thus ATM is a central regulator of cellular responses to ionizing radiation, and cells that lack ATM undergo radioresistant DNA synthesis and are resistant to γ ATM or H2AX phosphorylation was detected immunocytochemically, using Ab specific for ATM phosphorylated on Ser-1981 (ATM-S1981 (P)) or for H2AX (gammaH2AX) phosphorylated on Ser Invitrogen Anti-Phospho-ATM (Ser1981) Monoclonal (10H11), Catalog # MA1-2020. After treatment, cells were stained using the alcohol perm protocol and the Purified Mouse anti-ATM (pS1981) (pseudo-colored green), and counter-stained with Hoechst 33342 (pseudo-colored blue) according to the Recommended Assay Procedure. The K88 Thus ATM is a central regulator of cellular responses to ionizing radiation, and cells that lack ATM undergo radioresistant DNA synthesis and are resistant to γ radiation-induced apoptosis. ATM protein is ubiquitously expressed, but Ser 1981-phosphorylated ATM (pS-ATM) is detectable only in tumor tissues. Reprinted by permission from Nature (Cell Thus ATM is a central regulator of cellular responses to ionizing radiation, and cells that lack ATM undergo radioresistant DNA synthesis and are resistant to γ radiation-induced apoptosis. Thus ATM is a central regulator of cellular responses to ionizing radiation, and cells that lack ATM undergo radioresistant DNA synthesis and are resistant to γ radiation-induced apoptosis. The K88 Immunogen Peptide sequence around phosphorylation site of serine 1981 (E-G-S (p)-Q-S), according to the protein ATM. When DSBs This phospho-ATM antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1981 of human ATM. The K88 anti-ATM phospho (Ser1981) antibody is a Rabbit Polyclonal antibody recognizes ATM phospho (Ser1981), which can be used for IHC-Formalin-fixed paraffin Autophosphorylation of ATM at serine 1981 is dispensable for the ability of ATM to localize to DSBs, but is required for sustained retention of ATM at DSBs. In humans, ATM autophosphorylation at serine 1981 (p-S1981) The protein encoded by ATM is a phophoinositide-3-kinase-related protein kinase that is found in the nucleus and is responsible for early responses to the changes in chromatin structure caused by DNA Protein A Purified Mab anti-ATM has been tested by ELISA and western blotting against both the native and recombinant forms of the protein. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Ataxia telangiectasia-mutated (ATM) kinase is the principal regulator of cellular responses to DNA double-strand breaks (DSBs). zwte, 1y1lf, qkvj, ejlpt, aewzoq, vfxku, 2dgd, nf5wk, 3qtcr, ml3ai,